Worldwide, there are an estimated 180 million people with diabetes, and this population is expected to double by the year 2030 (1). In the U.S., 7% of the population (20.8 million people) have diabetes, and a further 73 million people are classified as pre-diabetic. Nearly 1 in every 400 children has type 1 diabetes and is insulin-dependent (2), and by age 60 about 20% of the population has type 2 diabetes.

The disease affects an increasing number of people each year and is increasingly costly to treat. It is important for diabetics to avoid high glycemic levels to prevent dangerous chronic conditions including heart disease, stroke, high blood pressure, blindness, kidney disease, amputations, dental diseases, pregnancy complications, sexual dysfunction, and nervous system disease (2). It is also crucial to avoid dangerously low glycemic levels associated with acute cognitive dysfunction. Current treatments, however, based on conventional monitoring methods, only approximate the function of the normal pancreas, and the blood glucose profiles of even the most diligent patients remain markedly abnormal.

The worldwide annual expenditure on home and self blood glucose monitoring products has been estimated at $4 billion with half of the sales occurring in the U.S. (3). The total economic cost of diabetes in the U.S. in 2002 was estimated at $132 billion and diabetes accounts for 11% of the total U.S. healthcare expenditure (2). The direct cost of diabetes has more than doubled in recent years and continues to grow.

With diabetes already affecting so many people, the prevalence of the disease increasing at a staggering rate, and conventional technologies inadequate for optimal treatment, there is significant need for advanced technology to monitor and treat the disease. GlySens will provide glucose monitors that meet this need and help people with diabetes better control their glucose levels.

1. World Health Organization Fact Sheet, September 2006.
2. American Diabetes Association, October 2006.
3. "Market Snapshot," Medical Device and Diagnostic Industry Magazine, February 2003.